Myasthenia gravis diagnosis and treatment in Noida. Dr. Kapil Singhal (DM AIIMS) at Medanta Hospital — AChR antibody, pyridostigmine, thymectomy coordination. Team Sushrut.
Dr Manish Vaish
Director & HOD – Neurosciences
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Overview
Symptoms
Title
Ptosis (drooping upper eyelid)
typically worse in the evening
Title
Diplopia (double vision)
Title
Difficulty chewing or swallowing (dysphagia, dysarthria)
Title
Facial weakness
expressionless face, nasal voice
Title
Limb weakness
proximal, fluctuating, worse with repetitive activity
Title
Respiratory muscle weakness
myasthenic crisis: emergency
Treatments
Title
Pyridostigmine (acetylcholinesterase inhibitor)
symptomatic first-line treatment
Title
Immunosuppression
prednisolone, azathioprine, mycophenolate
Title
Thymectomy (thymus removal)
beneficial in AChR-positive non-thymomatous MG under 60
Title
IVIG (intravenous immunoglobulin) for rapid improvement in crisis or pre-operatively
Title
Plasmapheresis for myasthenic crisis
Title
Avoidance of drugs that exacerbate MG
